Genomics of the brain and its disorders

We study how genetic variation shapes the nervous system — and how that knowledge can be turned into better diagnosis and treatment of neurological disease. Our work spans large-scale human genetics, multi-omics and deep clinical phenotyping.

Our research Get in touch

Invitation til CycloView

Du er det rigtige sted

CycloView (og CycloDay) udgår fra Neurogenomics-forskningsgruppen, som hører til både Dansk Hovedpinecenter og Translationelt Forskningscenter, Rigshospitalet. Vi står også bag denne hjemmeside, hvis formål er at kommunikere gruppens generelle forskning.

Hvis du har fået en invitation via Digital Post til CycloView, er den korrekt. Det er en del af en landsdækkende undersøgelse, hvor tilfældigt udvalgte kvinder i alderen 18 til 55 år inviteres til at svare på et spørgeskema om menstruationscyklussen. Du kan læse mere om projekterne på cyclome.dk.

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Research

From genetic variation to clinical insight

Neurological disease is common, heritable and mechanistically poorly understood. We work across five connected themes to close that gap.

Human disease genetics

Genome-wide association and sequencing studies in large clinical and population cohorts, to identify the variants and genes that carry risk for neurological disorders.

Multi-omics integration

Transcriptomics, methylation and proteomics layered onto genetic signals, so that an associated locus becomes a candidate gene, tissue and pathway rather than a coordinate.

Deep clinical phenotyping

Nationwide registries, hospital records and digital measures of cognition and symptom burden — phenotypes precise enough for the genetics to resolve.

Translation

Turning findings into usable tools: risk stratification, biomarkers and drug-target evidence that can be tested in the clinic.

Cyclome

A platform spanning several projects, built on understanding variation in the menstrual cycle and its biology — and how that variation relates to headache, pain, migraine and symptoms such as ADHD.

Team

The group

Publications

Recent work

Newest first, compiled automatically from the group members' ORCID records and Crossref metadata.

Contact

Get in touch

We welcome collaborations, and we are always glad to hear from prospective PhD students and postdocs with an interest in the genetics of neurological disease — write to us with a CV and a short note on what you would like to work on.

E-mail
thomas.folkmann.hansen@regionh.dk
Address
Translational Research Centre
Nordstjernevej 40-44
2600 Glostrup, Denmark
Affiliated with
Translational Research Centre · Danish Headache Center · Danish Center for Multiple Sclerosis · DTU · TUH